MICROBIAL RESISTANCE IN THE CURRENT CONTEXT AND THE IMPORTANCE OF KNOWLEDGE AND APPLICATION IN ANTIMICROBIAL POLICY

Microbial resistance in the current context and the importance of knowledge and application in antimicrobial policy

Introduction: The current resistance of germs to antimicrobials constitutes a serious health problem throughout the world.Mechanisms may be intrinsic or adaptive.The indiscriminate and irrational use of these drugs is the main cause of the gravity of the situation that is presented today.Objective: to carry out an updated review about of antibiotic

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The heparin-binding activity of secreted modular calcium-binding protein 1 (SMOC-1) modulates its cell adhesion properties.

Secreted Walking Belt modular calcium-binding proteins 1 and 2 (SMOC-1 and SMOC-1) are extracellular calcium- binding proteins belonging to the BM-40 family of proteins.In this work we have identified a highly basic region in the extracellular calcium-binding (EC) domain of the SMOC-1 similar to other known glycosaminoglycan-binding motifs.Size-exc

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Optimal pressure management in water distribution networks through district metered area creation based on machine learning

ABSTRACT Integrated management of water supply systems with efficient use of natural resources requires optimization of operational performances.Dividing the water supply networks into small units, so-called district metered areas (DMAs), is Coolers a strategy that allows the development of specific operational rules, responsible for improving the

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